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In the fictional universe of Star Trek, the Prime Directive (also known as "Starfleet General Order 1", and the "non-interference directive") is a guiding principle of Starfleet that prohibits its members from interfering with the natural development of alien civilizations. Its stated aim is to protect unprepared civilizations from the danger of starship crews introducing advanced technology, knowledge, and values before they are ready. Since its introduction in the first season of the original Star Trek series, the directive has featured in many Star Trek episodes as part of a moral question over how best to establish diplomatic relations with new alien worlds.

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