Christoph Cremer

Christoph Cremer

Christoph Cremer (born in Freiburg im Breisgau, Germany) is a German physicist and emeritus at the Ruprecht-Karls-University Heidelberg, former honorary professor at the University of Mainz and was a former group leader at Institute of Molecular Biology (IMB) at the Johannes Gutenberg University of Mainz, Germany, who has successfully overcome the conventional limit of resolution that applies to light based investigations (the Abbe limit) by a range of different methods (1971/1978 development of the concept of 4Pi-microscopy; 1996 localization microscopy SPDM; 1997 spatially structured illumination SIM (first developed in 1995 by John M. Guerra at Polaroid Corp.)). In the meantime, according to his own statement, Christoph Cremer is a member of the Max Planck Institute for Chemistry (Otto Hahn Institute) and the Max Planck Institute for Polymer Research. His actual microscope Vertico-SMI is the world's fastest nano light microscope that allows large scale investigation of supramolecular complexes including living cell conditions. It allows 3 D imaging of biological preparations marked with conventional fluorescent dyes and reaches a resolution of 10 nm in 2D and 40 nm in 3D. This nanoscope has therefore the potential to add substantially to the current revolution in optical imaging which will affect the entire molecular biology, medical and pharmaceutical research. The technology allows the development of new strategies for the prevention, the lowering of risk and therapeutic treatment of diseases.

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