SD may refer to:
Shacklesons Disease is a rare and unknown sickness that affects the brain. This disease is labeled as non-contagious and possibly fatal. The potential cause(s) are bacterial viruses which in times of stress in life causes it to react. As of Fall 2008, Scientists stated in the Medical Bulletin of Rare Diseases No. 4991, that Shacklesons Disease is non-curable and is under studies to uncover more detailed information about this miraculous disease.